Iyini i-lidocaine?

I-Lidocaine iyi-anesthesia yendawo, eyaziwa nangokuthi i-sirocaine, ethathe indawo ye-procaine eminyakeni yamuva futhi isetshenziselwa kakhulu izinzwa zokungena endaweni ekuhlinzeni izimonyo.Ivimbela ukuvuthwa kwezinzwa kanye nokuqhutshwa ngokuvimbela iziteshi ze-sodium ion kuma-membrane weseli ye-nerve.Ukuncibilika kwe-lipid nesilinganiso sokubophezela kwamaprotheni kuphezulu kune-procaine, enekhono eliqinile lokungena kweseli, ukuqala ngokushesha, isikhathi eside sokwenza okuthile, namandla esenzo aphindwe kane kune-procaine.

Izicelo zomtholampilo zihlanganisa i-anesthesia yokungena, i-epidural anesthesia, i-anesthesia yendawo (kuhlanganise ne-mucosal anesthesia ngesikhathi se-thoracoscopy noma ukuhlinzwa kwesisu), kanye ne-nerve conduction block.Ukuze kwandiswe isikhathi sokubulala izinzwa futhi kuncishiswe imiphumela engemihle efana nobuthi be-lidocaine, i-adrenaline ingafakwa ku-anesthetic.

I-Lidocaine ingasetshenziswa futhi ekwelapheni ukushaya kwe-ventricular ngaphambi kwesikhathi, i-ventricular tachycardia, ubuthi be-digitalis, i-ventricular arrhythmias ebangelwa ukuhlinzwa kwenhliziyo kanye ne-catheterization ngemva kwe-acute myocardial infarction, okuhlanganisa ukushaya kwe-ventricular ngaphambi kwesikhathi, i-ventricular tachycardia, kanye ne-ventricular fibrillation isetshenziselwa iziguli. abanesithuthwane esibeleselayo abangakwazi ukusebenzisa amanye ama-anticonvulsants kanye ne-anesthesia yendawo noma yomgogodla.Kodwa ngokuvamile ayisebenzi kuma-supraventricular arrhythmias.

Inqubekelaphambili yocwaningo ekufakweni kwe-perioperative intravenous of lidocaine infusion

Ukusetshenziswa ngezikhathi ezithile kwezidakamizwa ze-opioid kungase kubangele ukusabela okubi okuningi, okukhuthaza ucwaningo olujulile ngezidakamizwa ezidambisa ubuhlungu ezingezona i-opioid.I-Lidocaine ingenye yezidakamizwa ezidambisa ubuhlungu ezingezona i-opioid.Ukuphathwa kwe-lidocaine ngezikhathi zokusebenza kunganciphisa umthamo we-intraoperative yezidakamizwa ze-opioid, kudambise izinhlungu zangemva kokuhlinzwa, ukusheshisa ukutakula kwangemva kokuhlinzwa komsebenzi wamathumbu, kufinyeze ubude besikhathi sokuhlala esibhedlela futhi kukhuthaze ukuvuselelwa ngemuva kokuhlinzwa.

Ukusetshenziswa komtholampilo kwe-lidocaine ye-intravenous ngesikhathi sokuhlinzwa

1.Yehlisa impendulo yokucindezeleka ngesikhathi sokuhlinzwa kwe-anesthesia

2.nciphisa umthamo we-intraoperative wezidakamizwa ze-opioid, khulula ubuhlungu obungemuva kokuhlinzwa

3. Ukukhuthaza ukutholakala kokusebenza kwesisu, ukunciphisa izehlakalo zesicanucanu nokuhlanza ngemva kokuhlinzwa (PONV) kanye nokukhubazeka kwengqondo ngemva kokuhlinzwa (POCD), futhi kufinyeze ukuhlala esibhedlela

4.Eminye imisebenzi

Ngaphezu kwemiphumela engenhla, i-lidocaine nayo inemiphumela yokunciphisa ubuhlungu bomjovo we-propofol, ukuvimbela ukuphendula kokukhwehlela ngemva kokukhishwa, kanye nokunciphisa ukulimala kwe-myocardial.